The Hybribio Thalassemia GenoArray Diagnostic Kit is designed for detection of α-thalassemia and β-thalassemia from each blood sample. Biotinylated primers are designed for specific amplification of α-globin gene deletion / mutation regions and β-globin gene deletion / mutation region respectively.

Amplified DNA amplicons are then hybridized with the immobilized specific thalassemia probes located on the “HybriMem” under the US patented Flow-through Hybridization Technology. Enzyme immunoassay method is applied for color development in order to obtain test results to differentiate whether the patient is heterozygous or homozygous thalassemia gene carrier.